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Article

Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein.

Genesis (New York, N.Y. : 2000) - 1 Dec 2007

Lapinski Philip E, Bauler Timothy J, Brown Eric J, Hughes Elizabeth D, Saunders Thomas L, King Philip D

Abstract excerpt

p120 Ras GTPase-activating protein (RasGAP) encoded by the rasa1 gene in mice is a prototypical member of the RasGAP family of proteins involved in negative-regulation of the p21 Ras proto-oncogene. RasGAP has been implicated in signal transduction through a number of cell surface receptors. In h...

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Source

Identifiers

PMID: 18064675
DOI: 10.1002/dvg.20354

Genes

RASA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18064675-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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