Article
Polymorphisms of Two Indels at the PRNP Gene in Three Beef Cattle Herds.
Biochemical genetics - 1 Feb 2008
Kerber Alexandre R, Hepp Diego, Passos Daniel T, de Azevedo Weimer Tania
Abstract excerpt
Bovine spongiform encephalopathy (BSE) is a transmissible fatal neurodegenerative disorder, presenting a characteristic spongiform degeneration of cattle brain due to the accumulation of a pathogenic and protease-resistant infectious protein (prion). Two deletion/insertion polymorphisms of the prion protein gene (23 bp at the promoter region and 12 bp at intron 1) were analyzed in three beef cattle herds...
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