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Article

Evaluation of PRNP expression based on genotypes and alleles of two indel loci in the medulla oblongata of Japanese Black and Japanese Brown cattle.

PloS one - 1 Jan 2011

Msalya George, Shimogiri Takeshi, Ohno Shotaro, Okamoto Shin, Kawabe Kotaro, Minezawa Mitsuru, Maeda Yoshizane

Abstract excerpt

BACKGROUND: Prion protein (PrP) level plays the central role in bovine spongiform encephalopathy (BSE) susceptibility. Increasing the level of PrP decreases incubation period for this disease. Therefore, studying the expression of the cellular PrP or at least the messenger RNA might be used in selection for preventing the propagation of BSE and other prion diseases. Two insertion/deletion (indel) variations have...

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Identifiers

PMID: 21611160
DOI: 10.1371/journal.pone.0018787
PMCID: PMC3097178

Genes

PRNP

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Source receipt: pubmed, retrieved 7 Sept 2026.

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