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Article

Targeting c-KIT, PDGFR in cancer of unknown primary: a screening study for molecular markers of benefit.

Journal of cancer research and clinical oncology - 1 Jun 2008

Dova L, Pentheroudakis G, Golfinopoulos V, Malamou-Mitsi V, Georgiou I, Vartholomatos G, Ntemou A, Fountzilas G, Pavlidis N

Abstract excerpt

AIMS: In view of available targeted therapies, we investigated the presence of c-kit, PDGFR gene mutations and protein expression in cancer of unknown primary (CUP) in order to study their contribution in pathogenesis, their prognostic value and potential as therapeutic targets. METHODS: Mutation...

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Source

Identifiers

PMID: 18064489
DOI: 10.1007/s00432-007-0341-7

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18064489-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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