Article
Exploring the biology of cancer of unknown primary: breakthroughs and drawbacks.
European journal of clinical investigation - 1 May 2013
Kamposioras Konstantinos, Pentheroudakis George, Pavlidis Nicholas
Abstract excerpt
BACKGROUND: Cancer of unknown primary (CUP) ranks among the ten most common malignancies worldwide. Cancer of unknown primary presents as disseminated disease, has a dismal prognosis and remains a diagnosis of exclusion. The natural history and biology of the disease is poorly understood, and efforts are focused on identifying the specific 'CUP signature'. MATERIALS AND METHODS: We collected and analysed all...
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