Article
Expression of the <i>PDGF α‐receptor</i> 1.5 kb transcript, <i>OCT‐4</i>, and c‐<i>KIT</i> in human normal and malignant tissues. Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms
11 Feb 2002
Abstract excerpt
Human testicular germ cell tumours of adolescents and adults (TGCTs), including their precursor lesion carcinoma in situ (CIS), show expression of a 1.5 kb alternative transcript of the platelet-derived growth factor (PDGF) alpha-receptor gene. The so-called P2 promoter involved is located in intron 12 and its activity was found to be mutually exclusive with activity of the classical promoter (P1), which encodes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.