Article
Mutation analysis of BRAF, MEK1 and MEK2 in 15 ovarian cancer cell lines: implications for therapy.
PloS one - 5 Dec 2007
Estep Anne L, Palmer Chana, McCormick Frank, Rauen Katherine A
Abstract excerpt
BACKGROUND: Among gynecologic cancers, ovarian cancer is the second most common and has the highest death rate. Cancer is a genetic disorder and arises due to the accumulation of somatic mutations in critical genes. An understanding of the genetic basis of ovarian cancer has implications both for early detection and for therapeutic intervention in this population of patients. METHODOLOGY/PRINCIPAL FINDINGS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.