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Article

FGFR2 mutations are rare across histologic subtypes of ovarian cancer.

Gynecologic oncology - 1 Apr 2010

Byron Sara A, Gartside Michael G, Wellens Candice L, Goodfellow Paul J, Birrer Michael J, Campbell Ian G, Pollock Pamela M

Abstract excerpt

OBJECTIVE: Ovarian cancer is the leading cause of death from gynecologic malignancies in the Western world. Fibroblast growth factor receptor (FGFR) signaling has been implicated to play a role in ovarian tumorigenesis. Mutational activation of one member of this receptor family, FGFR2, is a frequent event in endometrioid endometrial cancer. Given the similarities in the histologic and molecular genetics of...

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Topics

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Share to Adenocarcinoma, Mucinous
Share to Carcinoma, Endometrioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystadenocarcinoma, Serous

Share to FGFR2 gene

Share to Mutation

Share to Ovarian Neoplasms

Share to Receptor, Fibroblast Growth Factor, Type 2

Source

Identifiers

PMID: 20106510
DOI: 10.1016/j.ygyno.2009.12.002

Genes

FGFR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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