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Article

Frequency of mutations and polymorphisms in borderline ovarian tumors of known cancer genes.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2013

Stemke-Hale Katherine, Shipman Kristy, Kitsou-Mylona Isidora, de Castro David G, Hird Vicky, Brown Robert, Flanagan James, Gabra Hani, Mills Gordon B, Agarwal Roshan, El-Bahrawy Mona

Abstract excerpt

Borderline ovarian tumors represent an understudied subset of ovarian tumors. Most studies investigating aberrations in borderline tumors have focused on KRAS/BRAF mutations. In this study, we conducted an extensive analysis of mutations and single-nucleotide polymorphisms (SNPs) in borderline ovarian tumors. Using the Sequenom MassArray platform, we investigated 160 mutations/polymorphisms in 33 genes involved...

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Topics

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Share to Adenocarcinoma, Mucinous
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

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Source

Open in PubMed Open full text

Identifiers

PMID: 23174937
DOI: 10.1038/modpathol.2012.194
PMCID: PMC3856435

Genes

BRAF
KRAS
ABCB1
CTNNB1
FGFR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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