Article
Targeted therapies and clinical trials in ovarian cancer.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Dec 2013
Dancey J
Abstract excerpt
Recent advances in molecular profiling have shown that cancers arising from the ovary are phenotypically and genetically heterogeneous. Within histologies, many mutations in druggable targets are uncommon in frequency but mutations leading to activation of specific signal transduction pathways are common. These results support the notion that different targeted agents should be prioritized for testing between and...
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