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Article

Gene-centric characteristics of genome-wide association studies.

PloS one - 5 Dec 2007

Dong Changzheng, Qian Ziliang, Jia Peilin, Wang Ying, Huang Wei, Li Yixue

Abstract excerpt

BACKGROUND: The high-throughput genotyping chips have contributed greatly to genome-wide association (GWA) studies to identify novel disease susceptibility single nucleotide polymorphisms (SNPs). The high-density chips are designed using two different SNP selection approaches, the direct gene-centric approach, and the indirect quasi-random SNPs or linkage disequilibrium (LD)-based tagSNPs approaches. Although all...

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PMID: 18060058
DOI: 10.1371/journal.pone.0001262
PMCID: PMC2092383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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