Article
Substantial genetic overlap between neurocognition and schizophrenia: genetic modeling in twin samples.
Archives of general psychiatry - 1 Dec 2007
Toulopoulou Timothea, Picchioni Marco, Rijsdijk Fruhling, Hua-Hall Mei, Ettinger Ulrich, Sham Pak, Murray Robin
Abstract excerpt
CONTEXT: The use of endophenotypes, biological traits that increase the liability to a disorder, represents one strategy to facilitate the detection of susceptibility genes for complex behavioral disorders such as schizophrenia. Establishing that a candidate trait is both heritable and linked genetically to schizophrenia is integral to its validity as an endophenotypic marker. Neurocognitive deficits are among...
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