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Article

PAX2 expression by HHV-8-infected endothelial cells induced a proangiogenic and proinvasive phenotype.

Blood - 1 Mar 2008

Fonsato Valentina, Buttiglieri Stefano, Deregibus Maria Chiara, Bussolati Benedetta, Caselli Elisabetta, Di Luca Dario, Camussi Giovanni

Abstract excerpt

In the present study, we evaluated whether infection of microvascular endothelial cells (HMECs) with HHV-8 can trigger the expression of PAX2 oncogene and whether PAX2 protein is involved in HHV-8-induced transformation of HMECs. We found that HHV-8 infection induced the expression of both the PAX2 gene and PAX2 protein in HMECs but failed to induce PAX2 protein in HMECs stably transfected with PAX2 antisense...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18056486
DOI: 10.1182/blood-2007-04-085555

Genes

PAX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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