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Article

Productive infection of HUVEC by HHV-8 is associated with changes compatible with angiogenic transformations.

European journal of histochemistry : EJH - 1 Jan 2000

Foglieni C, Scabini S, Belloni D, Broccolo F, Lusso P, Malnati M S, Ferrero E

Abstract excerpt

Kaposi's Sarcoma (KS) is an angioproliferative disease associated with human herpesvirus 8 (HHV-8) infection. We have characterized the morphologic and phenotypic modifications of HUVEC in a model of productive HHV-8 infection. HHV-8 replication was associated with ultra-structural changes, flattened soma and a loss of marginal folds and intercellular contacts, and morphologic features, spindle cell conversion...

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Share to Antigens, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Viral

Share to Herpesvirus 8, Human

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Share to Neovascularization, Pathologic

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Source

Identifiers

PMID: 16216813
DOI: 10.4081/954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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