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Article

Role of Pax2 in apoptosis resistance and proinvasive phenotype of Kaposi's sarcoma cells.

The Journal of biological chemistry - 6 Feb 2004

Buttiglieri Stefano, Deregibus Maria Chiara, Bravo Stefania, Cassoni Paola, Chiarle Roberto, Bussolati Benedetta, Camussi Giovanni

Abstract excerpt

In this study, we found that Kaposi's sarcoma cells but not human microvascular endothelial cells expressed PAX2, a gene coding for a transcription factor involved both in organogenesis and tumorigenesis. Moreover, Pax2 was frequently expressed, on spindle-shaped cells, in Kaposi's sarcoma lesions. We cloned PAX2 from Kaposi's sarcoma cells and obtained antisense and sense DNA. Transfection of Kaposi's sarcoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Sarcoma, Kaposi

Source

Identifiers

PMID: 14627715
DOI: 10.1074/jbc.M306824200

Genes

PAX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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