Unveiling the role of KSHV‐infected human mesenchymal stem cells in Kaposi's sarcoma initiation

doi:10.1002/jmv.29684

Article

Unveiling the role of KSHV‐infected human mesenchymal stem cells in Kaposi's sarcoma initiation

1 May 2024

Abstract excerpt

Kaposi's sarcoma (KS) may derive from Kaposi's sarcoma herpesvirus (KSHV)-infected human mesenchymal stem cells (hMSCs) that migrate to sites characterized by inflammation and angiogenesis, promoting the initiation of KS. By analyzing the RNA sequences of KSHV-infected primary hMSCs, we have identified specific cell subpopulations, mechanisms, and conditions involved in the initial stages of KSHV-induced...

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