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Article

Hhip regulates tumor-stroma-mediated upregulation of tumor angiogenesis.

Experimental & molecular medicine - 27 Jan 2017

Agrawal Vijayendra, Kim Dong Young, Kwon Young-Guen

Abstract excerpt

Tumor growth is governed by the coordinated action of various types of cells that are present in the tumor environment. Fibroblasts, which constitute a major fraction of the stroma, participate actively in various signaling events and regulate tumor development and metastasis. The Hedgehog (Hh) pathway plays an important role in promoting tumor malignancy via fibroblasts; however, the role of hedgehog interacting...

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Share to Cancer-Associated Fibroblasts
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28127049
DOI: 10.1038/emm.2016.139
PMCID: PMC5291840

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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