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Article

Mitochondria and aging: dilution is the solution.

Cell metabolism - 1 Dec 2007

Durieux Jenni, Dillin Andrew

Abstract excerpt

Metabolic component depletion in model systems results in life-span extension, which has been difficult to reconcile with human metabolic pathologies. Recently, Rea et al. (2007) have shown that mitochondrial electron transport chain RNAi phenotypes in the worm C. elegans are dose dependent, providing an alternative view of mitochondrial function in longevity and metabolic diseases.

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Identifiers

PMID: 18054312
DOI: 10.1016/j.cmet.2007.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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