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Article

xCT expression reduces the early cell cycle requirement for calcium signaling.

Cellular signalling - 1 Feb 2008

Lastro Michele, Kourtidis Antonis, Farley Kate, Conklin Douglas S

Abstract excerpt

Calcium has long been recognized as an important regulator of cell cycle transitions although the mechanisms are largely unknown. A functional genomic screen has identified genes involved in the regulation of early cell cycle progression by calcium. These genes when overexpressed confer the ability to bypass the G1/S arrest induced by Ca(2+)-channel antagonists in mouse fibroblasts. Overexpression of the...

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Identifiers

PMID: 18054200
DOI: 10.1016/j.cellsig.2007.10.030
PMCID: PMC2812064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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