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Article

Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression.

Cell death and differentiation - 1 May 2012

Lewerenz J, Sato H, Albrecht P, Henke N, Noack R, Methner A, Maher P

Abstract excerpt

Selecting neuronal cell lines for resistance against oxidative stress might recapitulate some adaptive processes in neurodegenerative diseases where oxidative stress is involved like Parkinson's disease. We recently reported that in hippocampal HT22 cells selected for resistance against oxidative...

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Identifiers

PMID: 22095285
DOI: 10.1038/cdd.2011.165
PMCID: PMC3321624

Genes

ATF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22095285-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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