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Article

Cytostatic drugs differentially affect phenotypic features of porcine coronary artery smooth muscle cell populations.

FEBS letters - 22 Dec 2007

Prunotto Marco, Bacchetta Marc, Jayaraman Swaminathan, Galloni Marco, Van Eys Guillaume, Gabbiani Giulio, Bochaton-Piallat Marie-Luce

Abstract excerpt

We studied the effects of cytostatic drugs on porcine coronary artery spindle-shaped (S) and rhomboid (R) smooth muscle cell (SMC) biological activities related to intimal thickening (IT) formation. Imatinib, and to a lesser extent curcumin, decreased proliferation of S- and R-SMCs and migratory and urokinase activities of R-SMCs more efficiently compared with cyclosporine plus rapamycin. Imatinib increased the...

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Identifiers

PMID: 18053813
DOI: 10.1016/j.febslet.2007.11.060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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