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Incudomalleal joint formation: the roles of apoptosis, migration and downregulation

1 Dec 2007

Abstract excerpt

BACKGROUND: The middle ear of mammals is composed of three endochondrial ossicles, the stapes, incus and malleus. Joints link the malleus to the incus and the incus to the stapes. In the mouse the first arch derived malleus and incus are formed from a single Sox9 and Type II collagen expressing condensation that later subdivides to give rise to two separate ossicles. In contrast the stapes forms from a separate...

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PMID: 18053235
DOI: 10.1186/1471-213x-7-134

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