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Joint formation in the middle ear: Lessons from the mouse and guinea pig

19 Jan 2006

Abstract excerpt

The malleus, incus and stapes form an ossicle chain in the mammalian middle ear. These ossicles are articulated by joints that link the chain together. In humans and mice, fusion of the ossicles leads to hearing loss. However, in the adult guinea pig the malleus and incus are normally found as a single complex. In this report, we investigate how the malleus and incus form during mouse and guinea pig development....

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PMID: 16425222
DOI: 10.1002/dvdy.20666

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