Article
Retinoic acid disturbs mouse middle ear development in a stage-dependent fashion.
Developmental biology - 1 Apr 1997
Mallo M
Abstract excerpt
The mammalian middle ear contains a chain of three ossicles, the malleus, incus, and stapes, that transmit into the inner ear the vibrations produced in the tympanic membrane by aerial sound. I show here that retinoic acid interferes with the formation of the middle ear in a stage-specific fashion. The malformations produced are derived from a retinoic acid-induced inhibition of the formation and/or migration of...
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