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IL-1RA VNTR and IL-1α 4845G>T polymorphisms and risk of idiopathic male infertility in Iranian men: A case-control study and an in silico analysis.

Andrologia - 1 Nov 2018

Zamani-Badi Tayyebeh, Nikzad Hossein, Karimian Mohammad

Abstract excerpt

This study aimed to investigate the association of IL-1RA VNTR and IL-1α 4845G>T polymorphisms with idiopathic male infertility followed by an in silico analysis. In a case-control study, we collected blood samples from 230 infertile and 230 healthy men. Genotyping of IL-1RA VNTR was performed by PCR whereas IL-1α 4845G>T was genotyped by polymerase chain reaction-restriction fragment length polymorphism. An in...

Topics

Adult
Amino Acid Sequence
Case-Control Studies
Computer Simulation
Humans
Infertility, Male
Interleukin 1 Receptor Antagonist Protein
Interleukin-1alpha
Iran
Male
Minisatellite Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 29968322
DOI: 10.1111/and.13081

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