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Is tumor necrosis factor-376A promoter polymorphism associated with susceptibility to multiple sclerosis?

Medicina - 1 Jan 2007

Kauffman Marcelo A, Morón Dolores González, Sandoval Gustavo, Sica Roberto E, Garcea Orlando, Villa Andrés M

Abstract excerpt

A single nucleotide polymorphism (SNP) at position -376 of the tumor necrosis factor alpha gene (TNFA) has been associated with susceptibility to multiple sclerosis (MS) in Spain. However, no association was found in populations from the USA and The Netherlands. Here we investigate the association between the TNFA-376A SNP and MS susceptibility in Argentinean patients with MS. The A/G genotype was found in 4.4%...

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PMID: 18051225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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