Article
Tumour necrosis factor alpha gene (TNF-alpha) -376 polymorphism in Hungarian patients with primary progressive multiple sclerosis.
Journal of neuroimmunology - 31 Mar 2009
Losonczi Erika, Bencsik Krisztina, Nagy Zsanett Fricska, Honti Viktor, Szalczer Estilla, Rajda Cecília, Illés Zsolt, Mátyás Klotild, Rózsa Csilla, Csépány Tünde, Füvesi Judit, Vécsei László
Abstract excerpt
Tumour necrosis factor alpha (TNF-alpha) is associated with clinical activity in relapsing-remitting multiple sclerosis (RRMS) and the development of progressive disease. Our aim was to investigate the TNF-alpha -376 polymorphism in primary progressive MS (PPMS) patients. Polymerase chain reaction and restriction fragment length polymorphism were carried out on 45 PPMS patients, 45 age and sex-matched RRMS...
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