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Article

Conversion of a replication origin to a silencer through a pathway shared by a Forkhead transcription factor and an S phase cyclin.

Molecular biology of the cell - 1 Feb 2008

Casey Laurieann, Patterson Erin E, Müller Ulrika, Fox Catherine A

Abstract excerpt

Silencing of the mating-type locus HMR in Saccharomyces cerevisiae requires DNA elements called silencers. To establish HMR silencing, the origin recognition complex binds the HMR-E silencer and recruits the silent information regulator (Sir)1 protein. Sir1 in turn helps establish silencing by st...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18045995
DOI: 10.1091/mbc.e07-04-0323
PMCID: PMC2230585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18045995-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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