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Article

A yeast-based phenotypic screen for aquaporin inhibitors.

Pflugers Archiv : European journal of physiology - 1 Jul 2008

Wu Binghua, Altmann Karin, Barzel Ina, Krehan Susanne, Beitz Eric

Abstract excerpt

Aquaporins mediate transport of water or small, uncharged solutes across cellular membranes according to the prevailing osmotic and chemical gradients. Because of their implication in human diseases and pathophysiological states, aquaporins are considered as potential drug targets. Yet, specific aquaporin inhibitors for in vivo studies are not available. Common functional aquaporin assays that monitor biophysical...

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PMID: 18043942
DOI: 10.1007/s00424-007-0383-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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