Article
Stem cells as common ancestors in a colorectal cancer ancestral tree.
Current opinion in gastroenterology - 1 Jan 2008
Shibata Darryl
Abstract excerpt
PURPOSE OF REVIEW: Cancer is thought to be an evolutionary process. Modern studies of evolution increasingly rely on genome comparisons, and similar molecular phylogeny approaches could be translated to somatic cell genomes to reconstruct colorectal cancer progression. The purpose of this review is to outline how human somatic cell ancestral trees can organize many old and new observations. RECENT FINDINGS: A...
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