Article
Molecular tumour clocks and colorectal cancer: seeing the unseen.
Pathology - 1 Dec 2002
Shibata Darryl
Abstract excerpt
Recent advances in mathematics and sequencing have revolutionised the analysis of evolution. Modern phylogeny is molecular phylogeny, or histories reconstructed from sequences. The same quantitative sequence approaches have not been fully translated to colorectal cancer. Molecular tumour clocks provide opportunities to reconstruct individual tumour histories. Phenotypic and genetic progression are usually thought...
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