Article
Nephropathy in type 1 diabetes is diminished in carriers of HLA-DRB1*04: the genetics of kidneys in diabetes (GoKinD) study.
Diabetes - 1 Feb 2008
Cordovado Suzanne K, Zhao Yuan, Warram James H, Gong Hongguang, Anderson Karen L, Hendrix Miyono M, Hancock Laura N, Cleary Patricia A, Mueller Patricia W
Abstract excerpt
OBJECTIVE: The purpose of this study was to examine whether known genetic risk factors for type 1 diabetes (HLA-DRB1, -DQA1, and -DQB1 and insulin locus) play a role in the etiology of diabetic nephropathy. RESEARCH DESIGN AND METHODS; Genetic analysis of HLA-DRB1, -DQA1, -DQB1 and the insulin gene (INS) was performed in the Genetics of Kidneys in Diabetes (GoKinD) collection of DNA (European ancestry subset),...
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