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Article

Identification of a common risk haplotype for diabetic nephropathy at the protein kinase C-beta1 (PRKCB1) gene locus.

Journal of the American Society of Nephrology : JASN - 1 Aug 2003

Araki Shin-Ichi, Ng Daniel P K, Krolewski Bozena, Wyrwicz Lucjan, Rogus John J, Canani Luis, Makita Yuichiro, Haneda Masakazu, Warram James H, Krolewski Andrzej S

Abstract excerpt

Abnormal activation of protein kinase C-beta isoforms in the diabetic state has been implicated in the development of diabetic nephropathy. It is thus plausible that DNA sequence differences in the protein kinase C-beta1 gene (PRKCB1), which encodes both betaI and betaII isoforms, may influence s...

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Identifiers

PMID: 12874455
DOI: 10.1097/01.asn.0000077347.27669.5c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12874455-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Identification of a common risk haplotype for diabetic nephropathy at the protein kinase C-beta1 (PRKCB1) gene locus.PMID 12874455Read ↗

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