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Article

Phenotypic mutation rates and the abundance of abnormal proteins in yeast.

PLoS computational biology - 1 Nov 2007

Willensdorfer Martin, Bürger Reinhard, Nowak Martin A

Abstract excerpt

Phenotypic mutations are errors that occur during protein synthesis. These errors lead to amino acid substitutions that give rise to abnormal proteins. Experiments suggest that such errors are quite common. We present a model to study the effect of phenotypic mutation rates on the amount of abnormal proteins in a cell. In our model, genes are regulated to synthesize a certain number of functional proteins. During...

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Identifiers

PMID: 18039025
DOI: 10.1371/journal.pcbi.0030203
PMCID: PMC2082502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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