Article
The look-ahead effect of phenotypic mutations.
Biology direct - 14 May 2008
Whitehead Dion J, Wilke Claus O, Vernazobres David, Bornberg-Bauer Erich
Abstract excerpt
BACKGROUND: The evolution of complex molecular traits such as disulphide bridges often requires multiple mutations. The intermediate steps in such evolutionary trajectories are likely to be selectively neutral or deleterious. Therefore, large populations and long times may be required to evolve s...
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