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Article

Mechanisms of potentiation of the mammalian GABAA receptor by the marine cembranoid eupalmerin acetate.

British journal of pharmacology - 1 Feb 2008

Li P, Reichert D E, Rodríguez A D, Manion B D, Evers A S, Eterović V A, Steinbach J H, Akk G

Abstract excerpt

BACKGROUND AND PURPOSE: Eupalmerin acetate (EPA) is a marine diterpene compound isolated from the gorgonian octocorals Eunicea succinea and Eunicea mammosa. The compound has been previously shown to modulate muscle-type and neuronal nicotinic acetylcholine receptors, which are inhibited in the presence of low micromolar concentrations of EPA. In this study, we examined the effect of EPA on another...

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Identifiers

PMID: 18037909
DOI: 10.1038/sj.bjp.0707597
PMCID: PMC2241790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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