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Article

The RIZ Pro704 insertion-deletion polymorphism, bone mineral density and fracture risk: the Rotterdam study.

Bone - 1 Feb 2008

Stolk Lisette, van Meurs Joyce B J, Arp Pascal P, Hofman Albert, Pols Huibert A P, Uitterlinden André G

Abstract excerpt

Estrogens play a major role in the maintenance of bone and bone strength, and they exert their effects via estrogen receptors. Recently, an estrogen receptor alpha (ESR1) specific co-activator, retinoblastoma-interacting zinc-finger protein (RIZ1, 1p36), was shown to strongly enhance ESR1 function in vitro. The same study showed that a Proline insertion-deletion polymorphism at amino acid position 704 (Pro704...

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Source

Identifiers

PMID: 18037365
DOI: 10.1016/j.bone.2007.10.008

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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