Article
ApoE gene polymorphisms, BMD, and fracture risk in elderly men and women: the Rotterdam study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2004
Schoofs Mariette W C J, van der Klift Marjolein, Hofman Albert, van Duijn Cornelia M, Stricker Bruno H Ch, Pols Huibert A P, Uitterlinden André G
Abstract excerpt
UNLABELLED: To study the association between the ApoE gene polymorphism and osteoporosis, we performed an association study in 5,857 subjects from the Rotterdam Study. We did not observe an association between the ApoE polymorphism and osteoporosis in this study, which is thus far the largest study on ApoE and osteoporosis. INTRODUCTION: The E*4 allele of the E*2, E*3, E*4 protein isoform polymorphism in the gene...
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