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Article

The 3' UTR IGF2R-A2/B2 variant is associated with increased tumor growth and advanced stages in non-small cell lung cancer.

Cancer letters - 8 Feb 2008

Kotsinas Athanassios, Evangelou Konstantinos, Sideridou Maria, Kotzamanis George, Constantinides Constantinos, Zavras Athanasios I, Douglass Chester W, Papavassiliou Athanasios G, Gorgoulis Vassilis G

Abstract excerpt

Normal function of insulin-like growth factor II receptor (IGF2R) gene has been associated with negative control of tumor growth in vivo and in vitro. Rare alleles at a 3' UTR short tandem repeat polymorphism of IGF2R are known to decrease transcript stability. One such allele (A2/B2) increases s...

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PMID: 18037232
DOI: 10.1016/j.canlet.2007.10.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18037232-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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