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Article

Insulin-like growth factor 1 pathway mutations and protein expression in resected non-small cell lung cancer.

Human pathology - 1 Jun 2014

Reinmuth Niels, Kloos Sebastian, Warth Arne, Risch Angela, Muley Thomas, Hoffmann Hans, Thomas Michael, Meister Michael

Abstract excerpt

The purpose of this study was to characterize the prevalence of insulin-like growth factor 1 receptor (IGF1R) mutations, single nucleotide polymorphisms (SNP), and protein overexpression in surgically resected non-small cell lung cancers in relation to patient characteristics and prognosis. This retrospective study was conducted on 304 patients with non-small cell lung cancers who underwent curative pulmonary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24745618
DOI: 10.1016/j.humpath.2014.01.010

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