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Article

MicroRNA‐494 suppresses cell proliferation and induces senescence in A549 lung cancer cells

13 Dec 2011

Abstract excerpt

OBJECTIVES: MicroRNAs (miRNAs) are small functional RNAs that regulate mRNAs for degradation or translational suppression. In the present study, we aimed to reveal functional importance of miRNA-494 (miR-494) in A549 human lung cancer cells. MATERIALS AND METHODS: We established A549 cells that constitutively expressed miR-494. Next, we sought to investigate insulin-like growth factor 2 mRNA-binding protein 1...

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PMID: 22151897
DOI: 10.1111/j.1365-2184.2011.00798.x

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