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Insulin-like growth factor 1 gene polymorphism in women with breast cancer.

Medical oncology (Northwood, London, England) - 1 Apr 2017

Costa-Silva Danylo Rafhael, da Conceição Barros-Oliveira Maria, Borges Rafael Soares, Campos-Verdes Larysse Maira, da Silva-Sampaio João Paulo, Escorcio-Dourado Carla Solange, Martins Luana Mota, Alencar Airlane Pereira, Baracat Edmund Chada, Silva Vladimir Costa, da Silva Benedito Borges

Abstract excerpt

Breast cancer is a disease of unknown etiology; however, the major risk factors are genetic alterations. Studies have demonstrated an association between insulin-like growth factor 1 (IGF-1) gene polymorphism and cell proliferation and reduced apoptosis, in addition to its role in breast cancer growth and aggressiveness. Two polymorphic variants of the IGF-1 gene are highlighted in association with breast cancer,...

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PMID: 28315227
DOI: 10.1007/s12032-017-0915-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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