Article
Association of catechol-O-methyltransferase variants with loudness dependence of auditory evoked potentials.
Human psychopharmacology - 1 Mar 2008
Juckel Georg, Kawohl Wolfram, Giegling Ina, Mavrogiorgou Paraskevi, Winter Christine, Pogarell Oliver, Mulert Christoph, Hegerl Ulrich, Rujescu Dan
Abstract excerpt
OBJECTIVE: The loudness dependence of auditory evoked potentials (LDAEP) provides a measure of the central serotonergic activity. As dopamine transporter availabilities also correlate with LDAEP, a dopaminergic influence is probable. The enzyme catechol-O-methyltransferase (COMT) is involved in the inactivation of synaptic dopamine. The aim of this study was to investigate the relationship between genetic...
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