Article
A561C polymorphism of E-selectin is associated with ischemic cerebrovascular disease in the Japanese population without diabetes mellitus and hypercholesterolemia.
Brain research - 7 Sept 2006
Hattori Hidenori, Sato Hideki, Ito Daisuke, Tanahashi Norio, Murata Mitsuru, Saito Ikuo, Watanabe Kiyoaki, Suzuki Norihiro
Abstract excerpt
E-selectin, which is a member of the selectin superfamily of adhesion molecules, contributes to the leukocyte-endothelial cell attachments and is involved in the pathogenesis of thrombovascular diseases as a consequence. We investigated the A561C mutation in the E-selectin gene in 235 Japanese patients with ischemic cerebrovascular disease (CVD) and 301 age- and sex-matched healthy controls. Excluding the...
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