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Article

A561C polymorphism of E-selectin is associated with ischemic cerebrovascular disease in the Japanese population without diabetes mellitus and hypercholesterolemia.

Brain research - 7 Sept 2006

Hattori Hidenori, Sato Hideki, Ito Daisuke, Tanahashi Norio, Murata Mitsuru, Saito Ikuo, Watanabe Kiyoaki, Suzuki Norihiro

Abstract excerpt

E-selectin, which is a member of the selectin superfamily of adhesion molecules, contributes to the leukocyte-endothelial cell attachments and is involved in the pathogenesis of thrombovascular diseases as a consequence. We investigated the A561C mutation in the E-selectin gene in 235 Japanese patients with ischemic cerebrovascular disease (CVD) and 301 age- and sex-matched healthy controls. Excluding the...

Topics

Aged
Brain Ischemia
Cell Adhesion
Cerebral Arteries
Cerebrovascular Disorders
Chemotaxis, Leukocyte
Diabetes Complications
E-Selectin
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hypercholesterolemia

Intracranial Thrombosis

Japan

Male

Middle Aged

Polymorphism, Genetic

Risk Factors

Source

Identifiers

PMID: 16843446
DOI: 10.1016/j.brainres.2006.06.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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