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Article

Groucho oligomerization is required for repression in vivo.

Molecular and cellular biology - 1 May 2004

Song Haiyun, Hasson Peleg, Paroush Ze'ev, Courey Albert J

Abstract excerpt

Drosophila Groucho (Gro) is a member of a family of metazoan corepressors with widespread roles in development. Previous studies indicated that a conserved domain in Gro, termed the Q domain, was required for repression in cultured cells and mediated homotetramerization. Evidence presented here suggests that the Q domain contains two coiled-coil motifs required for oligomerization and repression in vivo....

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Identifiers

PMID: 15121853
DOI: 10.1128/MCB.24.10.4341-4350.2004
PMCID: PMC400465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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