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Article

Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression.

BMC cancer - 21 May 2009

Arce Laura, Pate Kira T, Waterman Marian L

Abstract excerpt

BACKGROUND: Drosophila Groucho and its human Transducin-like-Enhancer of Split orthologs (TLEs) function as transcription co-repressors within the context of Wnt signaling, a pathway with strong links to cancer. The current model for how Groucho/TLE's modify Wnt signaling is by direct competition...

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Identifiers

PMID: 19460168
DOI: 10.1186/1471-2407-9-159
PMCID: PMC2701438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19460168-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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