Article
Local action of long-range repressors in the Drosophila embryo.
The EMBO journal - 1 May 2001
Nibu Y, Zhang H, Levine M
Abstract excerpt
Previous studies have identified two corepressors in the early Drosophila embryo: Groucho and dCTBP: Both proteins are recruited to the DNA template by interacting with short peptide motifs conserved in a variety of sequence-specific transcriptional repressors. Once bound to DNA, Groucho appears to mediate long-range repression, while dCtBP directs short-range repression. The short-range Krüppel repressor was...
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