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Article

The association between vascular function-related genes and age at natural menopause.

Menopause (New York, N.Y.) - 1 Jan 2000

van Disseldorp Jeroen, Broekmans Frank J, Peeters Petra H, Fauser Bart C, van der Schouw Yvonne T

Abstract excerpt

OBJECTIVE: In this study we attempted to confirm recent findings suggesting that age at natural menopause might be affected by single nucleotide polymorphisms in certain cardiovascular risk factor genes, such as genes encoding for blood clotting factors II, V, and VII and the apolipoprotein E2 gene. Such validation might increase support for the theory that ovarian aging is partly due to aging of the vascular...

Topics

Aging
Apolipoprotein E2
Blood Coagulation Factors
Female
Humans
Menopause
Middle Aged
Polymorphism, Single Nucleotide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 18030173
DOI: 10.1097/gme.0b013e31814cec52

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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