Article
Polymorphisms associated with thrombophilia and vascular homeostasis and the timing of menarche and menopause in 728 white women.
Menopause (New York, N.Y.) - 1 Jan 2000
Tempfer Clemens B, Riener Eva-Katrin, Keck Christoph, Grimm Christoph, Heinze Georg, Huber Johannes C, Gitsch Gerald, Hefler Lukas A
Abstract excerpt
OBJECTIVE: Genetic factors have been proposed as modulators of the timing of natural menopause. Single nucleotide polymorphisms (SNPs) of genes associated with thrombophilia and vascular homeostasis may interfere with ovarian function and thus are candidate genes for early menopause. We attempted to assess the association of SNPs and the timing of menarche and natural and surgical menopause in an ethnically...
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