Article
Identification of functional domains in Arabidopsis thaliana mRNA decapping enzyme (AtDcp2).
Nucleic acids research - 1 Jan 2008
Gunawardana Dilantha, Cheng Heung-Chin, Gayler Kenwyn R
Abstract excerpt
The Arabidopsis thaliana decapping enzyme (AtDcp2) was characterized by bioinformatics analysis and by biochemical studies of the enzyme and mutants produced by recombinant expression. Three functionally significant regions were detected: (i) a highly disordered C-terminal region with a putative PSD-95, Discs-large, ZO-1 (PDZ) domain-binding motif, (ii) a conserved Nudix box constituting the putative active site...
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